WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_RTAAACA_V$FREAC2_01       ID:DB_ID:2417
C=907; O=13; E=1.32; R=9.81; rawP=5.74e-10; adjP=1.49e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
2  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
3  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
4  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
5  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
6  ENSG00000135801 NA TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 27097 ENSG00000135801
7  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
8  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
9  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
10  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
11  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
12  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
13  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=17; E=3.58; R=4.75; rawP=5.22e-08; adjP=6.76e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
2  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
3  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
4  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
5  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
6  ENSG00000105339 NA DENND3 DENN/MADD domain containing 3 22898 ENSG00000105339
7  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
8  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367
9  ENSG00000158445 NA KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 3745 ENSG00000158445
10  ENSG00000099992 NA TBC1D10A TBC1 domain family, member 10A 83874 ENSG00000099992
11  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
12  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
13  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
14  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
15  ENSG00000198478 NA SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 83699 ENSG00000198478
16  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
17  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251


Database:Transcription Target       Name:hsa_V$IK3_01       ID:DB_ID:1904
C=221; O=6; E=0.32; R=18.59; rawP=9.01e-07; adjP=5.23e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
2  ENSG00000198478 NA SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 83699 ENSG00000198478
3  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052
4  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
5  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
6  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2250; O=15; E=3.29; R=4.56; rawP=6.24e-07; adjP=5.23e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
2  ENSG00000116016 NA EPAS1 endothelial PAS domain protein 1 2034 ENSG00000116016
3  ENSG00000152049 NA KCNE4 potassium voltage-gated channel, Isk-related family, member 4 23704 ENSG00000152049
4  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
5  ENSG00000099992 NA TBC1D10A TBC1 domain family, member 10A 83874 ENSG00000099992
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
8  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
9  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
10  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
11  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
12  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
13  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
14  ENSG00000130052 NA STARD8 StAR-related lipid transfer (START) domain containing 8 9754 ENSG00000130052
15  ENSG00000057704 NA TMCC3 transmembrane and coiled-coil domain family 3 57458 ENSG00000057704


Database:Transcription Target       Name:hsa_YNGTTNNNATT_UNKNOWN       ID:DB_ID:2392
C=361; O=7; E=0.53; R=13.27; rawP=1.01e-06; adjP=5.23e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143507 NA DUSP10 dual specificity phosphatase 10 11221 ENSG00000143507
2  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
3  ENSG00000152049 NA KCNE4 potassium voltage-gated channel, Isk-related family, member 4 23704 ENSG00000152049
4  ENSG00000132702 NA HAPLN2 hyaluronan and proteoglycan link protein 2 60484 ENSG00000132702
5  ENSG00000130222 NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
6  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
7  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:Transcription Target       Name:hsa_V$P300_01       ID:DB_ID:1863
C=248; O=6; E=0.36; R=16.56; rawP=1.76e-06; adjP=7.60e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000189120 NA SP6 Sp6 transcription factor 80320 ENSG00000189120
2  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
3  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
4  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
5  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
6  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209


Database:Transcription Target       Name:hsa_TTAYRTAA_V$E4BP4_01       ID:DB_ID:2411
C=256; O=6; E=0.37; R=16.04; rawP=2.11e-06; adjP=7.81e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000119138 NA KLF9 Kruppel-like factor 9 687 ENSG00000119138
2  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
3  ENSG00000111077 NA TENC1 tensin like C1 domain containing phosphatase (tensin 2) 23371 ENSG00000111077
4  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
5  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
6  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070


Database:Transcription Target       Name:hsa_V$AR_01       ID:DB_ID:2133
C=153; O=5; E=0.22; R=22.37; rawP=3.13e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
2  ENSG00000123933 NA MXD4 MAX dimerization protein 4 10608 ENSG00000123933
3  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
4  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
5  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672


Database:Transcription Target       Name:hsa_TTGTTT_V$FOXO4_01       ID:DB_ID:2416
C=2037; O=13; E=2.98; R=4.37; rawP=6.41e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168874 NA ATOH8 atonal homolog 8 (Drosophila) 84913 ENSG00000168874
2  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
3  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
4  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
5  ENSG00000196781 NA TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 7088 ENSG00000196781
6  ENSG00000120896 NA SORBS3 sorbin and SH3 domain containing 3 10174 ENSG00000120896
7  ENSG00000108551 NA RASD1 RAS, dexamethasone-induced 1 51655 ENSG00000108551
8  ENSG00000131634 NA TMEM204 transmembrane protein 204 79652 ENSG00000131634
9  ENSG00000164107 NA HAND2 heart and neural crest derivatives expressed 2 9464 ENSG00000164107
10  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
11  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263
12  ENSG00000168209 NA DDIT4 DNA-damage-inducible transcript 4 54541 ENSG00000168209
13  ENSG00000162367 NA TAL1 T-cell acute lymphocytic leukemia 1 6886 ENSG00000162367


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=15; E=4.22; R=3.55; rawP=1.35e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173825 NA TIGD3 tigger transposable element derived 3 220359 ENSG00000173825
2  ENSG00000185338 NA SOCS1 suppressor of cytokine signaling 1 8651 ENSG00000185338
3  ENSG00000179094 NA PER1 period homolog 1 (Drosophila) 5187 ENSG00000179094
4  ENSG00000099992 NA TBC1D10A TBC1 domain family, member 10A 83874 ENSG00000099992
5  ENSG00000092964 NA DPYSL2 dihydropyrimidinase-like 2 1808 ENSG00000092964
6  ENSG00000157514 NA TSC22D3 TSC22 domain family, member 3 1831 ENSG00000157514
7  ENSG00000100906 NA NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 ENSG00000100906
8  ENSG00000183779 NA ZNF703 zinc finger protein 703 80139 ENSG00000183779
9  ENSG00000213672 NA NCKIPSD NCK interacting protein with SH3 domain 51517 ENSG00000213672
10  ENSG00000168646 NA AXIN2 axin 2 8313 ENSG00000168646
11  ENSG00000068745 NA IP6K2 inositol hexakisphosphate kinase 2 51447 ENSG00000068745
12  ENSG00000163251 NA FZD5 frizzled family receptor 5 7855 ENSG00000163251
13  ENSG00000105643 NA ARRDC2 arrestin domain containing 2 27106 ENSG00000105643
14  ENSG00000084070 NA SMAP2 small ArfGAP2 64744 ENSG00000084070
15  ENSG00000118263 NA KLF7 Kruppel-like factor 7 (ubiquitous) 8609 ENSG00000118263




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).